Thesis Topics in Ophthalmology

Ophthalmology is an essential field of medicine that deals with the diagnosis and treatment of eye diseases. Since the modern society is affected by the negative influence of the technologies, people are constantly suffering from the eyes train and dry eye. Thesis topics in ophthalmology should represent the solid research in the sphere on the basis of strong evidence. While writing a thesis, one should pay the attention to the statistical measures in the field to address the methods and techniques of solving difficult medical tasks. Thesis topics in ophthalmology are significant for the examination of the urgent topics on eye diseases and discovery of the means of treating the eye conditions.

To begin with, due to the negative impact of computers and laptops, the majority of the individuals experience the eye pain and dry eye condition. This might be an important topic for discussion since it is estimated that millions of adults suffer from the dry eye. The controversies in ophthalmology have arisen over a long time concerning the etiology of dry eye and experience of pain. The evidence from other fields shows that alterations in the central nervous system exacerbate the irritative symptoms and eye pain. Sometimes the patient can complain about chronic pain syndrome that is characterized by the systemic pain.

Dry eye disease occurs in 5% to 35% of the world population and is more present in females. The condition has the severe consequences for the life quality negatively influencing the visual activity, productivity at work, social interaction, and physical functioning. The sources reveal that individuals with dry eyes of the moderate and severe degree have similar either social or psychological life as people experiencing angina of the same degree or those who made hospital dialysis. Dry eye condition is connected with the disorder of the tear film, meibomian glands, violation of normal ocular surface, and inflammation of the eye surface. The disease is accompanied by the huge discomfort, disturbance of tear film, and visual difficulties that might lead to the damage of the ocular surface. Patients suffering from dry eye disease have problems with focus because of the tear film osmolarity and ocular surface inflammation.

Corneal sensation remaining intact is essential to keep the healthy ocular surface as well as quality and quantity of tears because corneal nerves have the direct trophic impact on maintaining the corneal epithelium. Corneal confocal microscope (CCM) might be used to reflect the cornea involving the sub-basal nerve layer in people with dry eye disease. As a matter of fact, the condition can be triggered by the majority of mechanisms that result in the ocular irritation; however, it is still not understood what is the cause of dry eyes when the tears are normally produced and the ocular surface is moist enough.

To conclude, the discordant dry eye appears because of the tear production discordance and ocular surface staining. The processes in the central nervous system are interchangeably connected with the severe symptoms of eye strain and ocular surface damage. The further research should be done to relieve the symptoms and find the adequate treatment of the disease.

References

Bron, A. J., Tomlinson, A., Foulks, G. N., Pepose, J. S., Baudouin, C., Geerling, G., … & Lemp, M. A. (2014). Rethinking dry eye disease: a perspective on clinical implications. The ocular surface, 12(2), S1-S31.

Dry eye disease: risk factors and selecting treatment. (2015). The Pharmaceutical Journal. http://dx.doi.org/10.1211/pj.2015.20069420

Shtein, R. M., Harper, D. E., Pallazola, V., Harte, S. E., Hussain, M., Sugar, A & Clauw, D. J. (2016). Discordant dry eye disease (an American Ophthalmological Society thesis). Transactions of the American Ophthalmological Society, 114.

Sullivan, B. D., Crews, L. A., Messmer, E. M., Foulks, G. N., Nichols, K. K., Baenninger, P., … & Lemp, M. A. (2014). Correlations between commonly used objective signs and symptoms for the diagnosis of dry eye disease: clinical implications. Acta ophthalmologica, 92(2), 161-166.

Yun, C., Kang, S., Kim, H., & Song, J. (2012). Prevalence of Dry Eye Disease among University Students. Journal Of The Korean Ophthalmological Society, 53(4), 505. http://dx.doi.org/10.3341/jkos.2012.53.4.505

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